Transgenic Bcl-3 slows T cell proliferation
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چکیده
منابع مشابه
Transgenic Bcl-3 slows T cell proliferation
Immunological adjuvants, such as bacterial LPS, increase the mRNA levels of the IkB-related NF-kappaB transcriptional transactivator, Bcl-3, in activated T cells. Adjuvants also increase the life expectancy of activated T cells, as does over-expression of Bcl-3, suggesting that Bcl-3 is part of the pathway whereby adjuvants affect T cell lifespans. However, previous reports, confirmed here, sho...
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Background MicroRNAs are small and non-coding RNA molecules with approximately 22 nt in length that cause inhibition of translation or degradation of mRNA. MiR-155 is a kind of molecule with different functions, such as its role in proliferation, apoptosis, inflammation, differentiation, and immunity. One of its best known functions is apoptosis that affects on caspase-3 activity. The main aim...
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ژورنال
عنوان ژورنال: International Immunology
سال: 2009
ISSN: 0953-8178,1460-2377
DOI: 10.1093/intimm/dxp002